Characterising Lipid Lipolysis and Its Implication in Lipid-Based Formulation Development
نویسندگان
چکیده
منابع مشابه
Lipolysis and lipophagy in lipid storage myopathies
AIMS Triglycerides droplets are massively stored in muscle in Lipid Storage Myopathies (LSM). We studied in muscle regulators of lipophagy, the expression of the transcription factor-EB (TFEB) (a master regulator of lysosomal biogenesis), and markers of autophagy which are induced by starvation and exert a transcriptional control on lipid catabolism. METHODS We investigated the factors that r...
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Atorvastatin calcium, the lipid lowering agent, is taken as a model drug characterized by poor water solubility and bioavailability. In this study an attempt was made for preparation of nanocrystals using high pressure homogenization. A number of stabilizers were included as well as polymers at different concentrations, and the formulations were homogenized for ten cycles at a pressure of 1000 ...
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ژورنال
عنوان ژورنال: The AAPS Journal
سال: 2012
ISSN: 1550-7416
DOI: 10.1208/s12248-012-9398-6